Upon submission, in your cover letter, please include the names of at least five potential reviewers, in the relevant field of research, to review your manuscript. In light of this, please ensure that there are no conflicts of interest.
Call for Papers: Evolution of prokaryote virus defense
Biology Direct is calling for submissions to our Collection on Evolution of prokaryote virus defense. The Collection will explore areas under the umbrella of prokaryote virus defense evolution, including defense system discovery, defense system phylogeny, horizontal exchange of defense systems.
Call for Papers: Frontiers and Challenges in Structural Biology
Biology Direct welcomes submissions for a new Collection of structural biology articles. The Collection will include contributions with significant impact on understanding the architecture and function of biological macromolecules, advancing biological theory, and fostering biotechnological/medical applications.
Call for Papers: Bioinformatics Theory and Methods for Biological Discovery
Biology Direct is proud to announce a new Collection that aims to demonstrate innovative approaches addressing biological and medical challenges using computational techniques that support new engineering applications, analytic-method development, or mathematical foundations of biological systems.
Featured Article: CAP1: a novel extracellular vesicle marker linked to endothelial senescence in atherosclerosis
Endothelial dysfunction (ED) is recognized as a critical underlying condition of cardiovascular disease [1], in which about one-third affects those under the age of 70. Endothelial senescence (ES) is an aging-related response and a leading cause of ED by still unknown mechanisms. Our understanding of the misalignment between chronological and vascular aging must still be completed in this context. Establishing a distinct molecular signature of senescence can enhance our comprehension and potentially prevent vascular aging-related cardiovascular disease influencing ED [2], a primary etiological source of atherosclerosis.
Authors: Ignacio Hernandez, Laura Botana, Javier Diez-Mata, Laura Tesoro, Beatriz Jimenez-Guirado, Claudia Gonzalez-Cucharero, Nunzio Alcharani, Jose Luis Zamorano, Marta Saura & Carlos Zaragoza
Published: 06 April 2025
Additional Cover Letter Guidelines
Editor-in-Chief
Gerry Melino, University of Rome "Tor Vergata", Italy
Gerry Melino is Professor of Biochemistry at the Faculty of Medicine, University of Rome "Tor Vergata" and also at DZNE in Bonn, Germany. He is a member of the Academia Lincei as well as of the Academia Europaea. For 19 years he was programme leader at the Toxicology Unit of the Medical Research Council, Cambridge University, UK. His scientific interest focuses upon programmed cell death in cancer and skin. Gerry's major work investigates the p53 family members – p63 and p73. The molecular events driven by DNA damage to elicit the function of p63/p73 is investigated in vitro (transcriptional targets, proteosomal degradation, inhibitors) as well in ad hoc transgenic animal models.
Articles
-
-
Elucidation of short linear motif-based interactions of the MIT and rhodanese domains of the ubiquitin-specific protease 8
-
Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches
-
The role of IGF2BP2 in macrophage-mediated NLRP3 inflammasome activation in the pathogenesis of dry AMD
-
Integrating machine learning models with multi-omics analysis to decipher the prognostic significance of mitotic catastrophe heterogeneity in bladder cancer
-
The ancient Virus World and evolution of cells
-
The RNA world hypothesis: the worst theory of the early evolution of life (except for all the others)a
-
A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action
-
Is evolution Darwinian or/and Lamarckian?
-
The advantages and disadvantages of horizontal gene transfer and the emergence of the first species
2025
Evolution of prokaryote virus defense
Biology Direct
2024
Frontiers and Challenges in Structural Biology
Biology Direct
Bioinformatics Theory and Methods for Biological Discovery
Biology Direct
Plant Development and Environmental Interactions
Biology Direct
2023
Cancer Biology
Biology Direct
2020
Cancer pathways
Biology Direct
Collection published: 10 April 2020
Cancer prediction
Biology Direct
Collection published: 13 April 2020
COVID-19
Biology Direct
Collection published: 20 April 2020
Evolution
Biology Direct
Collection published: 21 April 2020
Microbiome research
Biology Direct
Collection published: 23 April 2020
2018
Proceedings of the Critical Assessment of Massive Data Analysis (CAMDA) Satellite Meeting to ISMB 2018
Biology Direct
Collection published: 13 February 2020
Part of: CAMDA Thematic Series
2017
Proceedings of the Critical Assessment of Massive Data Analysis (CAMDA) Satellite Meeting to ISMB 2017
Biology Direct
Collection published: 23 August 2019
Part of: CAMDA Thematic Series
2016
Evolution and cancer: A mathematical biology approach II
Biology Direct
Collection published: 23 August 2016
2015
Proceedings of the Critical Assessment of Massive Data Analysis (CAMDA) Satellite Meeting to ISMB 2015
Biology Direct
Collection published: 20 December 2016
Part of: CAMDA Thematic Series
2011
Beyond the tree of life
Biology Direct
Collection published: 30 June 2011
2010
Evolution and cancer: A mathematical biology approach
Biology Direct
Collection published: 20 April 2010
2009
Evolutionary Biology 150 years after the 'Origin': is a post-modern synthesis in sight?
Biology Direct
Collection published: 24 April 2009
2008
Origin and early evolution of life
Biology Direct
Collection published: 9 July 2008
Call for Papers: Bioinformatics Theory and Methods for Biological Discovery
Biology Direct is proud to announce a new Collection that aims to demonstrate innovative approaches addressing biological and medical challenges using computational techniques that support new engineering applications, analytic-method development, or mathematical foundations of biological systems.
Read MoreAnnual Journal Metrics
-
Citation Impact 2023
Journal Impact Factor: 5.7
5-year Journal Impact Factor: 4.5
Source Normalized Impact per Paper (SNIP): 1.060
SCImago Journal Rank (SJR): 1.161
Speed 2024
Submission to first editorial decision (median days): 3
Submission to acceptance (median days): 80
Usage 2024
Downloads: 705,596
Altmetric mentions: 615