Figure 5

(a) Solutions of system (9)–(10) with gamma distributed parameters β on [1, ∞) and δ on [1, ∞). Uninfected cells, X(t), infected cells, Y(t), and the total tumor load, X(t) + Y(t), are shown in blue, green and black, respectively. The initial means of the distributions are E _β (0) = 11 and E _δ (0) = 10, initial variances are ${\sigma }_{\beta }^2$ (0) = 8 and ${\sigma }_{\delta }^2$ (0) = 0.5. The initial conditions are X(0) = 0.5, Y(0) = 0.1, and γ = 1. (b) The parametric curve (E _β (t), E _δ (t)) in the parameter space (compare with Fig. 1b)