Figure 2
From: γ-MYN: a new algorithm for estimating Ka and Ks with consideration of variable substitution rates

Estimated ω when κ Y = 3.75 and κ R varies from 1 to 10 under negative selection. We obtained better ω estimates by introducing parameter α when orthologous genes are under negative selection with ω varying from 0.1 to 0.9. The canonical genetic code was used for simulated sequences with 1.6 million human codons.