Figure 1

Automaton evolution. (Reproduced from [17].) The temporal evolution of a typical cellular automaton after (a) t = 0, (b) t = 100, (c) t = 250 and (d) t = 300 generations. Shown are normal epithelial (grey), hyperplastic (pink), hyperplastic-glycolytic (green) and hyperplastic-glycolytic-acid-resistant (yellow) cells. Cells with other phenotypic patterns are shown as black.