Figure 10

Morphology and phenotypic distribution in tumor treated with chemotherapy followed by glucose competitor at step 72. Morphology and phenotypic distribution in tumor treated with chemotherapy followed by glucose competitor at step 72. A represents chemoresistance (red for resistant and green for sensitive), B represents hyperglycolysis (red for high and green for low glycolysis), C shows acid resistance (red for resistance to low pHe and green for sensitivity) and D shows quiescent cells (green) and proliferative (yellow). The extra generation without chemotherapy allows regrowth of sensitive population enough to encompass and delay growth of resistant cells.