Figure 2
From: The mechanistic and evolutionary aspects of the 2′- and 3′-OH paradigm in biosynthetic machinery
The second step of the aminoacylation reaction catalyzed by AspRS. The terminal 3′-OH ribose is positioned for attack on the aspartyl-adenylate carboxyl group. The positive-charged and class II invariant arginine contributes to the neutralization and stabilization of the aspartyl-adenylate phosphate group. PDB Code: 1C0A.