Fig. 9

Alterations in the central carbon and nitrogen metabolism. Low molecular mass compounds were isolated from cells of Synechocystis 6803 grown in NaCl-free BG11 medium or medium supplemented with 4% NaCl for 7 days. LC–MS/MS was used to estimate the relative levels (Y axis show fold changes, amount in cells from 0% NaCl cultivation (-) set to 1 and relative level at 4% NaCl ( +) is shown) of central metabolites as part of primary carbon and nitrogen metabolism. Shown are mean values from three biological replicates (details in Additional file 1: Table S10). Dotted arrows indicate that several enzymes are necessary to convert one metabolite into the other. The alteration in the compatible solute GG is shown in Fig. 6