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Fig. 6 | Biology Direct

Fig. 6

From: Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis

Fig. 6

DKK2 reduces proliferation and promotes apoptosis in NSCLC cells. DKK2 was overexpressed or silenced in A549 and HCC827 cells. a, b DKK2 expression after overexpression or knockdown, shown by RT-qPCR and Western blotting. c Proliferation measured by CCK-8 assay. d, e Proliferation measured by EdU assay. f, g Apoptosis measured by flow cytometry. h Levels of Wnt1, Wnt3A, and β-catenin proteins in transfected A549 and HCC827 cells (Control, OE-CTRL, OE- DKK2, si-CTRL, and si-DKK2), measured by western blotting. Data are presented as mean ± standard deviation. *P < 0.05; **P < 0.01; ***P < 0.001

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Biology Direct

ISSN: 1745-6150

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