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Fig. 4 | Biology Direct

Fig. 4

From: LncRNA RP11-620J15.3 promotes HCC cell proliferation and metastasis by targeting miR-326/GPI to enhance glycolysis

Fig. 4

Overexpression of RP11-620J15.3 promotes glycolysis and progression in HCC. A The expression of RP11-620J15.3 in Huh-7 and HCC-LM3 cells transfected with RP11-620J15.3 plasmid. B, C CCK-8 and colony-formation assay demonstrated the proliferation ability of Huh-7 and HCC-LM3 cells. D, E Scratch wound-healing assay and Transwell invasion assay showed the migration and invasion abilities of the cells. F–H Changes in the glycolysis-related metabolites in HCC cells overexpressing RP11-620J15.3. I Changes in the ECAR rate in HCC cells overexpressing RP11-620J15.3. J, K The mRNA and protein expression of the related lipogenic enzymes in Huh7 and HCC-LM3 cells overexpressing RP11-620J15.3. *p < 0.05, **p < 0.01, ***p < 0.001

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Biology Direct

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