Fig. 5

ZNF488 upregulation of SCD1 promotes xenografted tumorigenesis. Ctrl, ZNF488 overexpressing and ZNF488 + shSCD1 PANC-1 stable cells lines were subcutaneously implanted into the nude mice for tumorigenesis. A The macroscopical images of tumors collected from the nude mice 37 days after cells implantation. B, C Tumor volume and body weight of the mice were monitored during tumorigenesis. D Tumors were weighted after sacrificing the mice. *p < 0.05. **p < 0.01