Fig. 7

Effect of 5 µM Gd³⁺ on I_L and I_Ca,L in K⁺ _in/K⁺ _out (A), Cs⁺ _in/K⁺ _out (B), K⁺ _in/Cs⁺ _out (C), and Cs⁺ _in/Cs⁺ _out (D) solutions. Control curves in blue: I_L – triangles and I_Ca,L – circles. Curves in the presence of Gd³⁺ in red: I_L – triangles and I_Ca,L – circles. Note: C: Switching cell perfusion from K⁺ _in/K⁺ _out solution (I_L – black triangles and I_Ca,L – black circles) to K⁺ _in/Cs⁺ _out solution (I_L – blue triangles and I_Ca,L – blue circles), followed by the application of Gd³⁺ (I_L – red triangles and I_Ca,L – red circles). While Gd³⁺ exerts only a minor effect on I_L, it eliminates I_Ca,L in all solutions tested