Fig. 6
From: PHF5A promotes esophageal squamous cell carcinoma progression via stabilizing VEGFA
PI3K/AKT signaling is required for PHF5A regulation on ESCC cells. (A) The PI3K/AKT signaling pathway was inhibited with PHF5A knockdown in Eca-109 cells and this effect was attenuated by AKT activator (SC79, 5 µM). GAPDH was used as the loading control. (B) The synergistic effects of PHF5A and AKT activator on Eca-109 cell apoptosis and (C) cell cycle was evaluated by flow cytometer. *p < 0.05, **p < 0.01, ***p < 0.001