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Fig. 3 | Biology Direct

Fig. 3

From: PLAU promotes growth and attenuates cisplatin chemosensitivity in ARID1A-depleted non-small cell lung cancer through interaction with TM4SF1

Fig. 3

The interaction with PLAU increases the stability of TM4SF1. (A, B) Co-immunoprecipitation assays using anti-PLAU antibody in ARID1A-depleted A549 (A) and H1299 (B) cells. (C) Western blot analysis of TM4SF1 protein levels in A549 and H1299 cells transfected with indicated plasmids. (D, E) NSCLC cells were transfected with vector or PLAU-expressing plasmid and treated with CHX for the indicated time intervals. TM4SF1 protein levels were quantified by Western blot analysis. *P < 0.05. (F) NSCLC cells were transfected with indicated shRNAs and tested for PLAU and TM4SF1 protein levels by Western blot analysis

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