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Fig. 6 | Biology Direct

Fig. 6

From: Comprehensive analysis of mitochondria-related genes indicates that PPP2R2B is a novel biomarker and promotes the progression of bladder cancer via Wnt signaling pathway

Fig. 6

Construction of a prognostic signature based on DEGs between BC patients with low or high PPP2R2B expressions. A Differential Expression Analysis: A total of 761 DEGs were identified in BC patients with either high or low PPP2R2B expression levels. B KEGG Pathway Enrichment Analysis of 761 DEGs. C LASSO regression was performed, and the coefficients of the 11 selected DEGs were determined. D The model achieved the best fit when considering 11 out of the 19 DEGs. E The risk score formula was established based on the coefficients of the 11 selected DEGs. F The high-risk group, determined by the risk score model, exhibited significantly poorer overall survival compared to the low-risk group. G ROC analysis was conducted to evaluate the prognostic model's performance over time

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Biology Direct

ISSN: 1745-6150

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