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Table 1 Demographic, clinicopathological and technical characteristics of the included ccRCC patients

From: Identification of novel snoRNA-based biomarkers for clear cell renal cell carcinoma from urine-derived extracellular vesicles

  

Discovery cohort (RNA-seq)

Validation cohort (qPCR)

Parameter

Category

Number [n]

Percentage [%]

Number [n]

Percentage [%]

gender

male

36

77

36

67

 

female

11

23

18

33

age (years)

median (range)

64 (40–80)

65 (40–80)

obesity (BMI ≥ 30)

yes

12

26

16

30

no

35

74

38

70

hypertension

yes

30

64

33

61

no

14

30

17

31

tumor stage

pT1

32

68

38

70

 

pT2

4

9

5

9

 

pT3

9

19

9

17

 

pT4

2

4

2

4

Lymph node stage

c/pN0

23

49

28

52

 

c/pN1

2

4

2

4

 

c/pNx

22

47

24

44

Metastasis stage

c/pM0

21

45

27

50

 

c/pM1

2

4

2

4

 

c/pMx

24

51

25

46

tumor grade

G1

7

15

10

19

 

G2

32

68

33

61

 

G3

6

13

9

17

 

G4

2

4

2

4

urine volume (ml)

median (range)

60 (20–110)

59 (20–110)

RNA yield (ng)

median (range)

29 (7-304)

32 (7-2196)

  1. The RNA-seq discovery cohort comprised n = 47 of 63 and the qPCR validation cohort n = 54 ccRCC patients of a total of 78 test subjects. The table shows the absolute and relative distribution of gender, age and clinicopathological parameters