Fig. 2
From: Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging
AMPK activity is essential for mouse oocyte maturation quality. (A) The representative images of MII oocyte morphology in the control, aging, aging + COM C groups. The oocytes showed normal polar body in the control group; however, there were fragment oocytes after maturation in the aging oocytes; while more proportion of oocytes in the aging oocytes treated with AMPK inhibitor COM C. Bar = 50 μm. (B) The percentage of fragmentation of oocytes in the control, aging, aging + COM C groups. *p < 0.05. (C) The representative images of oocytes in the control and COM C groups. Bar = 20 μm. (D) The percentage of polar body extrusion in the oocytes of the control and COM C groups. *p < 0.05