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Fig. 5 | Biology Direct

Fig. 5

From: CircHIF1A induces cetuximab resistance in colorectal cancer by promoting HIF1α-mediated glycometabolism alteration

Fig. 5

miR-361-5p intervention reverses circHIF1A-mediated Cetuximab resistance (Cetuximab 5 µg/mL). A-B. Effect of miR-361-5p downregulation on the proliferation (A) and colony formation (B) of LIM1215-R with circHIF1A downregulated. C-D. IF showed changes in the positive levels of Ki67 (C) and EdU (D) after miR-361-5p downregulation. E-F. Effect of miR-361-5p downregulation on mitochondrial metabolism (E) and glycolysis (F) in LIM1215-R. *P < 0.05, **P < 0.01, ***P < 0.001

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Biology Direct

ISSN: 1745-6150

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