Skip to main content
Fig. 6 | Biology Direct

Fig. 6

From: CircHIF1A induces cetuximab resistance in colorectal cancer by promoting HIF1α-mediated glycometabolism alteration

Fig. 6

HIF1A intervention reverses circHIF1A-mediated Cetuximab resistance (Cetuximab 5 µg/mL). A-B. Effect of HIF1A overexpression on the proliferation (A) and colony formation (B) of LIM1215-R with circHIF1A downregulated. C-D. IF showed changes in the positive levels of Ki67 (C) and EdU (D) after HIF1A overexpression. E-F. Effect of HIF1A overexpression on mitochondrial metabolism (E) and glycolysis (F) in LIM1215-R. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page

Biology Direct

ISSN: 1745-6150

Contact us