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Table 2 Univariate and multivariate cox proportional hazard model for disease free survival (DFS) and overall survival (OS) for TNBC patients

From: YY1 mediated DCUN1D5 transcriptional activation promotes triple-negative breast cancer progression by targeting FN1/PI3K/AKT pathway

Variables

Univariate analysis

Multivariate analysis

DFS

OS

DFS

OS

HR (95% CI)

Pa

HR (95% CI)

Pa

HR (95% CI)

Pa

HR (95% CI)

Pa

Age (years)

 

 ≤ 50

Reference

 

Reference

     

 > 50

0.96 (0.57–1.61)

0.865

1.28 (0.67–2.45)

0.464

    

Tumor size

 

 ≤ 2 cm

Reference

 

Reference

     

 > 2 cm

1.46 (0.83–2.56)

0.185

1.43 (0.72–2.84)

0.311

    

Lymph nodes metastasis

 

 No

Reference

 

Reference

 

Reference

 

Reference

 

 Yes

1.98 (1.16–3.36)

0.026

2.16 (1.12–4.17)

0.022

1.75 (1.02–3.01)

0.042

1.86 (0.95–3.62)

0.069

Grade

 

 I + II

Reference

 

Reference

     

 III

1.38 (0.78–2.44)

0.164

1.61 (0.78–3.33)

0.198

    

Lymphovascular invasion

     

 No

Reference

 

Reference

     

 Yes

1.52 (0.90–2.56)

0.121

1.50 (0.78–2.86)

0.223

    

DCUN1D5 expression

 

 Low

Reference

 

Reference

 

Reference

 

Reference

 

 High

2.09 (1.22–3.59)

0.008

2.55 (1.28–5.08)

0.008

1.87 (1.08–3.25)

0.026

2.27 (1.13–4.57)

0.022

  1. Abbreviation: HR: hazard ratio; CI: confidence interval
  2. a The P value was adjusted by the univariate Cox proportional hazard regression model