Variables | Univariate analysis | Multivariate analysis | ||||||
---|---|---|---|---|---|---|---|---|
DFS | OS | DFS | OS | |||||
HR (95% CI) | Pa | HR (95% CI) | Pa | HR (95% CI) | Pa | HR (95% CI) | Pa | |
Age (years) | Â | |||||||
 ≤ 50 | Reference |  | Reference |  |  |  |  |  |
 > 50 | 0.96 (0.57–1.61) | 0.865 | 1.28 (0.67–2.45) | 0.464 |  |  |  |  |
Tumor size | Â | |||||||
 ≤ 2 cm | Reference |  | Reference |  |  |  |  |  |
 > 2 cm | 1.46 (0.83–2.56) | 0.185 | 1.43 (0.72–2.84) | 0.311 |  |  |  |  |
Lymph nodes metastasis | Â | |||||||
 No | Reference |  | Reference |  | Reference |  | Reference |  |
 Yes | 1.98 (1.16–3.36) | 0.026 | 2.16 (1.12–4.17) | 0.022 | 1.75 (1.02–3.01) | 0.042 | 1.86 (0.95–3.62) | 0.069 |
Grade | Â | |||||||
 I + II | Reference |  | Reference |  |  |  |  |  |
 III | 1.38 (0.78–2.44) | 0.164 | 1.61 (0.78–3.33) | 0.198 |  |  |  |  |
Lymphovascular invasion | Â | Â | Â | Â | Â | |||
 No | Reference |  | Reference |  |  |  |  |  |
 Yes | 1.52 (0.90–2.56) | 0.121 | 1.50 (0.78–2.86) | 0.223 |  |  |  |  |
DCUN1D5 expression | Â | |||||||
 Low | Reference |  | Reference |  | Reference |  | Reference |  |
 High | 2.09 (1.22–3.59) | 0.008 | 2.55 (1.28–5.08) | 0.008 | 1.87 (1.08–3.25) | 0.026 | 2.27 (1.13–4.57) | 0.022 |