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Fig. 6 | Biology Direct

Fig. 6

From: Hypoxia-induced activation of HIF-1alpha/IL-1beta axis in microglia promotes glioma progression via NF-κB-mediated upregulation of heparanase expression

Fig. 6

Hypoxic microglia-secreted IL-1β contributes to glioma cell proliferation, migration, and invasion via NF-κB-mediated upregulation of HPSE expression. (A and B) The viability of U251 and U87 cells was estimated by CCK8 assay. (C) The proliferation ability of U251 and U87 cells was investigated by EdU assay. (D) Wound healing assay was implemented to appraise the migration ability of U251 and U87 cells. (E) Transwell assay was accomplished to appraise the invasion ability of U251 and U87 cells. n = 3. *P < 0.05, **P < 0.01, ***P < 0.001

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Biology Direct

ISSN: 1745-6150

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