Fig. 4
From: The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1
OTUD6B overexpression promotes LUAD progression. A The relative OTUD6B mRNA level was verified by qPCR in cells overexpressing OTUD6B and in the Kong vector-transfected LUAD cell line. B–D Cell proliferation was examined by the CCK8 assay and plate colony formation assay. E, F The sizes of tumors generated from normal LUAD cells (Vector-A549) and OTUD6B-overexpressing LUAD cells (OTUD6B-A549) in a mouse model. G, H The volume and weight of tumors generated from normal LUAD cells (Vector-A549) and OTUD6B-overexpressing LUAD cells (OTUD6B-A549) in the mouse model. I The expression of Ki-67 in mouse tumors was detected by immunohistochemistry. The data are presented as the means ± SD. *P < 0.05; **P < 0.01; ***P < 0.001