Fig. 2

Silencing of YTHDC1 inhibited the proliferation, migration, invasion and tube formation ability of RVECs. RT-qPCR analysis (A) and western blot (B) were used to detect the mRNA and protein expression of YTHDC1 in different groups. (C) CCK-8 kit was used to detect the cell viability. (D) Wound healing assay was applied to detect the migration in different groups. (E) The invasion in different group was assessed using transwell experiment. (F) Tube formation experiment was used to detect the angiogenic ability. Data were expressed as mean ± SD, n = 3. ^*P < 0.05, vs. NC group, ^#P < 0.05, ^##P < 0.01, vs. HG + si-NC group