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Fig. 2 | Biology Direct

Fig. 2

From: Neuregulin-4 protects cardiomyocytes against high-glucose-induced ferroptosis via the AMPK/NRF2 signalling pathway

Fig. 2

Nrg4 attenuates ferroptosis in DCM mice. A Representative TEM images depicting mitochondria in myocardial tissue, with arrows indicating mitochondria. B–F Western blot and quantitative analysis of ferroptosis-related proteins (TFR1, GPX4, ACSL4 and SLC7A11) in each group. G Comparison of Fe2 + in each group. H The content of the lipid peroxidation product MDA in each group. I The content of GSH in each group. J GSH/GSSG ratios in each group. The data are presented as the means ± SDs; n = 6; *P < 0.05, **P < 0.01, and ***P < 0.0001; ns, not significant

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