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Fig. 1 | Biology Direct

Fig. 1

From: METTL3 in cancer-associated fibroblasts-derived exosomes promotes the proliferation and metastasis and suppresses ferroptosis in colorectal cancer by eliciting ACSL3 m6A modification

Fig. 1

CAFs promote CRC cell proliferation, invasion and migration,and suppress cell ferroptosis. (A-H) LoVo and HCT-116 cells were incubated with PBS, NF-CM or CAF-CM for 48 h. (A, B) MTT and colony formation assays for cell proliferation analysis. (C-F) Detection analysis of cell migration and invasion using transwell and wound healing assays. (G, H) Western blotting analysis for PCNA and MMP9 protein levels. Technical replicates (n = 3), biological replicates (n = 3), *P < 0.05

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Biology Direct

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