Fig. 3

Regulation of the PI3K/AKT signaling pathway in Ishikawa cells by SAMHD1. (A): Note (A) Expression analysis of EMT-related molecules post SAMHD1 overexpression using qRT-PCR; (B) EMT-related molecule expression analysis post SAMHD1 overexpression using Western blot; (C) Changes in signaling pathways like PI3K, AKT, etc., post SAMHD1 overexpression at the cellular level analyzed through Western blot; data presented as mean ± standard deviation, with analysis conducted using independent sample t-test and cell experiments repeated 3 times). * denotes significance at p < 0.05 compared to the oe-NC group