Fig. 4

Cell-cell communications among three cell subsets. A Number of interactions in Normal and IVDD groups by heat map. B Number of interactions in Normal and IVDD groups by circle diagram. C Relative information flow in two groups. D Differences in communication signals emitted by chondrocyte between the Normal and IVDD groups. E Differences in communication signals emitted by Stromal cell between the Normal and IVDD groups. F Differences in communication signals emitted by Macrophage between the Normal and IVDD groups