Fig. 5
From: ZFP64 drives glycolysis-mediated stem cell-like properties and tumorigenesis in breast cancer
Glycolysis is involved in the role of ZFP64 in BC through RNA-seq analysis. (A) Schematic diagram of MCF-7 cells subjected to mRNA-seq. (B) Volcano plot of the differentially expressed genes. (C) Column diagram showing the enriched KEGG pathway from the upregulated genes. (D) Chord diagram showing the enriched GO terms from the upregulated genes. (E) An enrichment network generated from GSEA combined with GO analysis showing biological processes regulated by ZFP64. The red nodes represent upregulated biological pathways, the blue nodes represent downregulated biological pathways, and the blue lines represent gene overlap between pathways. (F) GSEA combined with GO analysis showing ZFP64 related to the Glycolytic process. (G) GSEA combined with KEGG analysis showing ZFP64 related to Glycolysis/Gluconeogenesis