Fig. 4

Temporal profiling of relative abundances reveals consistent trends in AD SGBs. MetaPhlAn 4 profiling unveils consistent temporal trends in a few AD microbiome species, which comprises both SGBs and those yet to be classified. Species consistently increasing with AD mouse aging include Parvibacter caecicola and Neglectibacter sp. X4, while Candidatus Arthromitus sp. SFB-mouse and several uSGBs display a decreasing trend over time