Fig. 8

Effects of FXR1 knockdown, or PDZK1IP1 and ATOH8 overexpression on the growth of human ESCA xenograft tumors in nude mice. (A) The representative tumor samples from each group are shown. (B) The tumor weight of human ESCA xenograft tumors was measured (n = 5). (C) The tumor volumes of human ESCA xenograft tumors were measured (n = 5). (D) The inhibition rate of tumor growth was calculated (n = 5). (E) Representative photographs of CD31, Ki67, and cleaved caspase-3 staining in human ESCA xenograft tumors (original magnification ×400). The PI, MVD, and AI were calculated (n = 3). Data are presented as mean ± SEM. * p < 0.05, ** p < 0.01 compared with the control group