Fig. 5

The effect of METTL4 and MARCKSL1 on tumor progression. A–B, SiRNA down-regulates the METTL4 expression in Hep3B and Huh7 cells. C-D, CCK-8 assays for Hep3B and Huh7 cells transfected with METTL4 siRNA-2 or the control. E, Transwell invasion assays for Hep3B and Huh7 cells transfected with METTL4 siRNA-2 or the control. Scale bars = 100 μm. F-G, SiRNA down-regulates the MARCKSL1 expression in Hep3B and Huh7 cells. H-I, CCK-8 assays for Hep3B and Huh7 cells transfected with MARCKSL1 siRNA-1 or the control. J, Transwell invasion assays for Hep3B and Huh7 cells transfected with MARCKSL1 siRNA-1 or the control. Scale bars = 100 μm. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001. NS, Not Significant