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Fig. 6 | Biology Direct

Fig. 6

From: Integrating Circle-Seq with transcriptomics reveals genome-wide characterization of extrachromosomal circular DNA for dilated cardiomyopathy

Fig. 6

Integrated analysis of eccDNAs and mRNAs. A Cluster heat map of dysregulated eccDNAs. B Cluster heat map of dysregulated mRNAs. C Summary data of dysregulated eccDNAs, mRNAs and dysregulated eccDNAs associated protein-coding genes. D Venn diagram shows the overlapping part of dysregulated mRNAs and dysregulated eccDNAs associated protein-coding genes. E The chromosomal location of upregulated eccDNAs (red circle) and mRNAs (red cross). F The chromosomal location of downregulated eccDNAs (blue circle) and mRNAs (blue cross). G EccDNA counts per gene relative to average transcription level of control (red cross) and DCM (blue cross) groups. H Dysregulated eccDNA counts per gene relative to average transcription level of control (red cross) and DCM (blue cross) groups. I GO enrichment analysis of dysregulated eccDNAs. J KEGG pathway enrichment analysis of dysregulated eccDNAs

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