Fig. 2
From: Telomeres: an organized string linking plants and mammals
Telomeres organization in plants: (A) Arabidopsis telomeres are coated by a smaller number of proteins representing the mammalian orthologue of TRFs and POTs proteins (TRB1, TRB2, TRB3, POT1a and POT1b) binding the 5’-TTTAGGG-3’ repeats. CST complex (CTC1-STN1-TEN1) is conserved among mammals and plants. (B) Ku70/Ku80 heterodimer binds blunt-ended chromosome termini. (C-D) Arabidopsis shelterins-like TRBs are composed of proteins containing a Myb-domain, that bind telomeric dsDNA, and containing OBs-folds (POT1s), that bind telomeric ssDNA. About TRF/TRB proteins, only the Myb-domain (red) appear to be conserved in both mammals and plants. About POT1 proteins, both OB1- and OB2-folds (orange) appear to be shared among mammals and plants. Both mammals and plant telomeres possess both euchromatic and heterochromatic epigenetic marks. (E) Arabidopsis RuvBLs proteins are tethered to telomerase complex by association with TRBs, differently from the human ones in which Pontin/Reptin associate with TERT and Dyskerin