Fig. 1
From: Active enhancers: recent research advances and insights into disease
Typical characteristics of enhancers in different states. A Inactive enhancers are in closed chromatin without transcription factors binding or characteristic histone modifications. B Primed enhancers solely have H3K4me1 marks, ready for activation. C Poised enhancers are marked by the activating H3K4me1 and the repressive H3K27me3. D Active enhancers have H3K4me1 and H3K27ac modifications, bind TFs, recruit coactivators, and form E-P loops