Skip to main content
Fig. 2 | Biology Direct

Fig. 2

From: Sorafenib-induced macrophage extracellular traps via ARHGDIG/IL4/PADI4 axis confer drug resistance through inhibiting ferroptosis in hepatocellular carcinoma

Fig. 2

The role of METs in sorafenib resistance in HCC. A Tumor photos and B tumor weight in Hepa1-6 model of HCC. NC: negative control with saline treatment. Sora: treatment with sorafenib. DNase I: treatment with DNase I. Sora + DNase I: treatment with sorafenib and DNase I. C Individual and D grouped tumor growth curve in Hepa1-6 model of HCC. E Tumor volume in Hepa1-6 model of HCC on day 25 after the first subcutaneous injection. F Survival of Hepa1-6 model of HCC. n = 6 B–F. Statistical significance was calculated by one-way analysis of variance (ANOVA), followed by Tukey’s multiple comparisons test B and E, and Log-rank (Mantel-Cox) test. Data represent the mean ± standard deviation (SD) of ≥ three independent experiments. *, p < 0.05; **, p < 0.01; ***, p < 0.001

Back to article page

Biology Direct

ISSN: 1745-6150

Contact us