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Fig. 2 | Biology Direct

Fig. 2

From: RNF19A inhibits bladder cancer progression by regulating ILK ubiquitination and inactivating the AKT/mTOR signalling pathway

Fig. 2

The overexpression of RNF19A suppressed cell proliferation, migration, invasion and the EMT process in BCa cells. (A) qRT‒PCR analysis of RNF19A mRNA expression in T24 and 5637 cells stably overexpressing RNF19A. (B-C) western blot analysis of RNF19A protein levels in T24 and 5637 cells overexpressing RNF19A and a quantitative analysis. (D-G) After RNF19A was overexpressed, cell proliferation was assessed via CCK-8 and colony formation assays. (H-K) After RNF19A was overexpressed, cell migration and invasion abilities were evaluated via wound healing and transwell invasion assays. (L-O) Protein levels of EMT-related markers (E-cad, N-cad, and Vim) in BCa cells stably overexpressing RNF19A. *P < 0.05, **P < 0.01, and ***P < 0.001

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Biology Direct

ISSN: 1745-6150

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