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Fig. 2 | Biology Direct

Fig. 2

From: Machine learning-driven estimation of mutational burden highlights DNAH5 as a prognostic marker in colorectal cancer

Fig. 2

Machine learning-based TMB estimation model building and evaluation. (a) The waterfall plot of TMB-related genes in patients with CRC, showing the top 30 genes ranked by mutation rate. (b) Box plots show the selected number of genes and the corresponding R2 scores based on the Lasso model. (c) Growth curves of the mean R2 values for different TMB estimation models. (d) The scatter plot shows the number of genes and the corresponding mean R2 values for the eight TMB estimation models when they tend to stabilize

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