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Fig. 2 | Biology Direct

Fig. 2

From: YTHDF2 promotes anaplastic thyroid cancer progression by activating the DDIT4/AKT/mTOR signaling pathway

Fig. 2

YTHDF2 promoted ATC malignant phenotype progression. A-C Effect of YTHDF2 on ATC proliferation detected by clonal colony formation assay, EdU assay, and CCK-8 assay. D F-actin fluorescent staining measurement of the effect of YTHDF2 overexpression and knockdown on cell cytoskeleton. Representative images of the F-actin fluorescent staining are shown. Scale bar = 10 μm. E, F Trans-well assay and wound healing assay to verify the effect of YTHDF2 knockdown and overexpression on cell migration ability. G Flow cytometry assay to confirm the apoptosis analysis induced by YTHDF2 knock-down and overexpression. Error bars represent the SD from at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001

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Biology Direct

ISSN: 1745-6150

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