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Fig. 8 | Biology Direct

Fig. 8

From: USP44 regulates HEXIM1 stability to inhibit tumorigenesis and metastasis of oral squamous cell carcinoma

Fig. 8

HEXIM1 mediates the antitumor effects of USP44 in OSCC cells. (A) Expression of HEXIM1 in CAL-27 cells transfected with the indicated shRNA plasmids and detected using Western blotting and RT-qPCR, respectively. (B) CCK-8 assays showing that cell viability was enhanced in HEXIM1-silenced CAL-27 cells. (C) Transwell assays analyzing the migration and invasion capabilities of CAL-27 cells with HEXIM1 silence. Quantification of migration and invasion cells was shown in the histograms. (D) Effect of HEXIM1 silencing on cell viability in CAL-27 cells overexpressing USP44. Cells were transfected with the indicated plasmids and the viability was determined by CCK-8 assay. (E) Effect of HEXIM1 silencing on cell migration and invasion capabilities in CAL-27 cells overexpressing USP44. Cells were transfected with the indicated plasmids. The migration and invasion capabilities were determined using Transwell assays. Quantification of migration and invasion cells was shown in the histograms

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Biology Direct

ISSN: 1745-6150

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