The RRP9-JUN axis promotes breast cancer progression via the AKT signalling pathway

Biology Direct

Table 2 Relationship between RRP9 expression and tumor characteristics in patients with breast cancer

Features	No. of patients	RRP9 expression		p value
Features	No. of patients	low	high	p value
All patients	110	53	57
Age (years)				0.082
≤ 57	59	33	26
> 57	51	20	31
Grade				0.355
II	59	26	33
III	51	27	24
AJCC stage				0.979
I	1	1	0
II	16	9	7
III	63	27	36
IV	30	16	14
Size and extent of primary tumour(T)				0.047
0	1	1	0
1	28	17	11
2	71	32	39
3	10	3	7
Regional lymph node metastasis(N)				0.563
0	52	25	27
1	32	13	19
2	16	8	8
3	10	7	3
ER nuclear positive				0.504
< 1%	43	19	24
≥ 1%	67	34	33
PR nuclear positive				0.648
< 20%	77	36	41
≥ 20%	33	17	16
HER2 testing results of membrane				0.031
3+	25	11	14
2+	23	9	14
1+	25	13	12
0	37	20	17
HER2 FISH data				0.875
negative	76	37	39
positive	34	16	18
Ki-67 nuclear positive				0.020
< 20%	80	44	36
≥ 20%	30	9	21
P53 nuclear test results				0.569
< 4	55	28	27
≥ 4	55	25	30
Molecular subtype				0.113
Luminal A	33	20	13
Luminal B	30	13	17
HER2 positive	21	10	11
Triple-negative	26	10	16
Molecular subtype				0.126
Luminal A	33	20	13
Triple-negative	26	10	16
Molecular subtype				0.874
Luminal B	30	13	17
Triple-negative	26	10	16
Molecular subtype				0.367
HER2 positive	21	10	11
Triple-negative	26	10	16

ISSN: 1745-6150