Fig. 3
From: PTGES3 proteolysis using the liposomal peptide-PROTAC approach
The ablation of PTGES3 decreased the tumor growth in vivo. (A) Images of implanted tumors from nude mice injected with Hep3B and Huh7 cells subcutaneously (n = 5). (B) Western blotting measured the PTGES3 expression in tumor samples (n = 5). (C) Immunohistochemical (IHC) staining of PTGES3 protein in implanted tumors with stable transfection by shNC or shPTGES3 (n = 5). (D) Tumor weight of nude mice (n = 5). (E) Tumor volume of nude mice (n = 5)