Fig. 5
From: PTGES3 proteolysis using the liposomal peptide-PROTAC approach
Preparation and characterization of PTGES3 liposome peptide-proteolysis targeting chimera (p-PROTAC). (A) Schematic diagram of the PTGES3 liposome p-PROTAC platform. (B) Particle size distribution of PTGES3 degrader liposomes collected via DLS. (C) Zeta potential of PTGES3 degrader liposomes (n = 3). (D) Stability of PTGES3 degrader liposomes in vitro in presence of serum and various enzymes (n = 3). (E) Stability of PTGES3 degrader liposomes Stored at 4 °C for 3 Months (n = 3). (F) Transmission electron microscope picture of PTGES3 degrader liposomes (n = 3)