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Fig. 1 | Biology Direct

Fig. 1

From: Integrative in-silico and in-vitro analysis of taurine and vitamin B12 in modulating PPARγ and Wnt signaling in hyperhomocysteinemia-induced osteoporosis

Fig. 1

The figure demonstrates PPARγ and its relation to signaling pathways. The panel A shows PPARγ as the molecular switch between adipogenesis and osteogenesis; B demonstrates the mechanism by which PPARγ agonists target the methodical inhibition of osteoblastogenesis and initiation of osteoclastogenesis; and C denotes the important helices H3, H4/5, H11 and H12 targeted by agonists and antagonists of PPARγ and in addition to them the β-sheets which are targeted by partial agonists and inverse agonists

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Biology Direct

ISSN: 1745-6150

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