Fig. 14

Validating in-silico observations using the mRNA expression of the genes of the prominent negative regulators of Wnt signaling pathway. The panels A, B represents the gene expression profiles for A PPARγ and B SOD1 in LPS-stimulated RAW 264.7 macrophages. In the plots antagonist of PPARγ (GW9662) are labelled as negative control (NC) and the agonist of PPARγ (pioglitazone hydrochloride) are shown as positive control (PC). The results are expressed as mean ± SEM (n = 3)