Fig. 4

The figure shows the results of the MD simulation trajectory. The plots in figure A- C represent the A RMSD of the apo-PPARγ (Apo-P), taurine-bound PPARγ (P–T), and homocysteine-bound PPARγ (P–H). The RMSD of B the DNA binding domain (DBD) and C the ligand binding domain (LBD) of PPARγ was also analyzed separately for the apo-PPARγ and compounds bound to PPARγ