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Fig. 6 | Biology Direct

Fig. 6

From: TFAP2C-mediated transcriptional activation of STEAP3 promotes lung squamous cell carcinoma progression by regulating the β-catenin pathway

Fig. 6

STEAP3 knockdown inhibits tumor growth. (A) The nude mice were administered the stable transfectants via subcutaneous injection. Tumor volumes were measured on a weekly basis from day 7 onwards. (B) On day 35, the tumors were excised and weighed. (C) The expression levels of STEAP3, PCNA, and Ki-67 in tumor tissues were determined by immunohistochemistry. Scale bar represents 50 μm. (D) The protein levels of STEAP3, PCNA, and Ki-67 in tumor tissues were quantified by western blot analysis. β-actin was employed as the internal control. (E) The levels of β-catenin protein in the cytoplasm and nucleus of tumor tissues were quantified by western blot analysis. β-actin was employed as the internal control. **P < 0.01

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Biology Direct

ISSN: 1745-6150

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