Fig. 6

Analysis of the Tumor Microenvironment Utilizing the LPRS Signature. (A) UMAP plot visualization of cell subtypes across 21 HCC patients. (B) UMAP plot depicting the density of LPRS. (C) Violin plots representing the LPRS value across different cell types. (D) UMAP plot illustrating the annotations of hepatocyte cells in an HCC patient. (E) UMAP plot showing the density of LPRS in hepatocyte subgroups. (F) Violin plots of LPRS values in various hepatocyte subgroups. (G-H) Heatmaps displaying the distribution of genes from the 8-gene LPRS model within the cellular subtypes of the HCC microenvironment