Fig. 2

FGI clustering analysis on TCGA pan-cancer RNA-Seq data. A t-SNE plot of 54 FGI gene clusters generated from 26 tumor types. B Clustering heatmap using GSVA scores of FGI gene clusters for samples of 26 tumor types. C Examples of tissue specific FGI gene clusters (liver and brain), showing boxplot of GSVA scores of clusters in tumor samples. D Examples of functional FGI gene clusters (cell cycle and lymphocyte activation), showing boxplot of GSVA scores of clusters in tumor samples. E Examples of positional FGI gene clusters, showing cluster names and gene distributions on chromosomes. F GSVA score violin plot of cluster_1 genes in male and female samples from TCGA