Fig. 3

FGI visualization after gene cluster annotation. A t-SNE plot of fully annotated FGI gene clusters from 26 tumor types. Some annotations with long names are put outside the plot. The inset is a small version of Supplemental Fig. S1A where clustered with similar functions were merged. Positional clusters are marked by the cluster number with additional letter “P”. B Distribution of functional and positional clusters on the FGI map, with a Venn diagram showing overlaps of three types of clusters. C Example of FGI mapping applied to three individual cases of tumor samples from different cancer types