Fig. 5
From: Matrix Metalloproteinase-9 is associated with tumor microenvironment remodeling of bladder cancer
GSEA for normal and BLC tissues with different MMP9 expressions, TIC profile in tumor samples and correlation analysis. (A) The most leading gene-rich sets were shown in Hallmark [31] collection with samples highly expressing MMP9, and NOM p < 0.05 and FDR < 0.06 were set to be the significance filtering threshold. (B) The gene-rich sets in tissues expressing MMP9 lowly. (C) Barplot indicated the constitute of TICs in 22 types in BLC tissues. (D) Heatmap indicated the association of TICs. The figures represented the p value of association between two TICs. Pearson coefficient was chosen to set the significance filtering threshold