Table 2 Top ten (by p-value) differentially expressed proteins between the heavier and leaner co-twins in the BMI-discordant pairs (n = 48 pairs/96 individuals). The paired co-twin analysis model was adjusted for smoking status
UniProt ID | UniProt Entry Name | Gene symbol | Protein name | Fold Change | p value | FDR p value |
|---|---|---|---|---|---|---|
P01023 | A2MG_HUMAN | A2M | Alpha-2-macroglobulin | 0.91 | 3.60E-06 | 5.78E-04 |
Q15848 | ADIPO_HUMAN | ADIPOQ | Adiponectin | 0.85 | 5.78E-06 | 5.78E-04 |
Q9BRJ7 | TIRR_HUMAN | NUDT16L1 | Tudor-interacting repair regulator protein | 1.17 | 7.54E-06 | 5.78E-04 |
P05452 | TETN_HUMAN | CLEC3B | Tetranectin | 1.15 | 9.23E-05 | 4.37E-03 |
O95568 | MET18_HUMAN | METTL18 | Histidine protein methyltransferase 1 homolog | 1.25 | 1.06E-04 | 4.37E-03 |
P10721 | KIT_HUMAN | KIT | Mast/stem cell growth factor receptor Kit | 1.26 | 1.14E-04 | 4.37E-03 |
O15360 | FANCA_HUMAN | FANCA | Fanconi anemia group A protein | 0.89 | 2.82E-04 | 9.25E-03 |
A0A0U1RQE8 | GLYLB_HUMAN | GLYATL1B | Putative glycine N-acyltransferase-like protein 1B | 1.19 | 3.40E-04 | 9.78E-03 |
O95251 | KAT7_HUMAN | KAT7 | Histone acetyltransferase KAT7 | 1,14 | 4.22E-04 | 1.08E-02 |
Q9HCM2 | PLXA4_HUMAN | PLXNA4 | Plexin-A4 | 1,13 | 4.68E-04 | 1.08E-02 |